The acute and dermal toxicity of antiparasitic salt briquettes on laboratory animals

Link to full russian text
Download PDF format

THE ACUTE AND DERMAL TOXICITY OF ANTIPARASITIC SALT BRIQUETTES ON LABORATORY ANIMALS

N.B. Yemelyanova

The acute toxicity of salt briquettes with ivermectin is investigated. LD50 for white rats is 6400 mg/kg, white mice – 10300 mg/kg (8945÷10854). At drawing on the intact leather (skin) of rats LD50 makes more than 12500 mg/kg. The salt briquettes with ivermectin have no irritating action on rats at unitary drawing.

Keywords: salt briquettes, toxicity, mice, rats, LD50, irritating action.


© 2016 The Author(s). Published by All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K.I. Skryabin.
This is an open access article under the Agreement of 02.07.2014 (Russian Science Citation Index (RSCI) and the Agreement of 12.06.2014 (CABI.org / Human Sciences section).