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Cestodocide activity of supramolecular complexes of albendazole at sheep.
Archipov I.A., Sadov K.M., Dolgoshev V.A., Sadova A.K., Glamazdin I.I., Varlamova A.I., Halikov S.S., Dushkin A.V., Chistyachenko Yu.S. All-Russian K.I. Skryabin Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants, Samara Scientific Research Veterinary Station, A.N. Nesmeyanov Institute of Organoelement Compounds RAS (INEOS RAS), Institute of Solid State Chemistry and Mechanochemistry SB RAS.
Summary. The supramolecular complexes of albendazole prepared according to mechanochemical technology using target delivery (Drug Delivery System) showed the high cestodocide efficacy at sheep spontaneously infected by Moniezia spp. The efficacy of supramolecular complexes of albendazole was 7-10-fold higher compared with albendazole.