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ACTION OF TRICHLABENDAZOLE IN THE SYSTEM “PARASITE – HOST”
Archipov I.A., Koshevarov N.I., Musaev M.V., Bibik O.I., Michailicin F.S.All-Russian K.I. Skryabin Institute of Helminthology, Kemerovo State Medcal Academy, Institute of Medical Parasitology and Tropical Medicine.
Summary.
Trichlabendazole is highly effective against imaginal and inmature Fasciola hepatica. It’s efficacy at dose levels of 7,5; 10 and 12,5 mg/kg of body weight appears to be 94,3; 100 and 100% against adult specimen and 92,4; 99,2 and 100% against inmature specimens respectively. The agent at dose levels of 10 (the therapeutic one) and 30 (the 3-fold one) is safe for sheep. Thichlabendazole causes nectrotic reactions in genital organs and disturbances in spermatogenesis of Fasciola.
© 2015 The Author(s). Published by All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K.I. Skryabin.
This is an open access article under the Agreement of 02.07.2014 (Russian Science Citation Index (RSCI) and the Agreement of 12.06.2014 (CABI.org / Human Sciences section).