Russian Journal of Parasitology
DOI:10.12737/13277
Article history:
Received 23.03.2015
Accepted 29.06.2015
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EFFICACY OF NEW BROAD SPECTRUM ANTHELMINTIC DRUGS FOR TREATMENT OF HELMINTHOSIS IN CATTLE IN CONDITIONS OF VOLOGDA REGION
Kryazhev A. L. 1, Nikitin V. F. 2
1 The Vologda State Dairy Farming Academy named after N.V. Vereshchagin,
e-mail: kamarnett@mail.ru
2 All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K.I. Skryabin, 117218 Russia, 28 B. Cheremushkinskaya st.
e-mail: nikitin@vniigis.ru
Abstract
Objective of research: to study the efficacy of new broad spectrum anthelmintic drugs for tre ating main helminthosis in cattle.
Materials and methods: 4 experiments were conducted to test the anthelmintic drugs used against helminthosis in cattle in conditions of Vologda region. In the fist experiment were involved 125 animals with fasciolosis divided into different groups by 25 animals in each group which got the single doses of: fascocide at a dose of 10 mg/kg, helmicide - 5,25 mg/kg according to the active ingredient, albendazole - 15 mg/kg, fezol - 14 mg/kg, alben - 10 mg/kg
The efficacy of preparations was registered according to the results of coproovoscopy before and 45 days after dehelmintization. The second experiment was performed at paramphistomosis in cattle with the use of the same preparations. In the 3, 4 and 5 experiments we used the same preparations at moniesiosis, strongylatozis of the digestive tract and dictyocaulosis in young cattle, respectively.
Results and discussion: at fasciolosis of cattle the drug efficacy was: for fascocide and helmicide - 100 %, fezol - 92, alben - 76 %, at paramphistomosis 100 %, 84, 80 and 68 %, respectively. The drug efficacy at cattle moniesiosis was: of helmicide and fezol - 100 %, alben - 92 %, and at gastro-intestinal strongylatozis: of fezol- 100 %, helmicide - 92 and alben - 84 %. At dictyocaulosis the efficacy was: of helmicide - 88 %, fezol – 92 and alben - 80 %.
Keywords: anthelmintic drugs, helminthosis , therapy, cattle.References
1. Arhipov I. A. Antigel'mintiki: farmakologiya i primenenie [Anthelmintics: pharmacology and uses]. Moscow , 2009. 405 p.
2. Kryazhev A.L. Distribution of helminthosis in cattle in Vologda region. Mater. dokl. nauch. konf. Vseros. o-va gel'mintol. RAN «Teorija i praktika bor'by s parazitarnymi boleznjami». [Proceedings of scientific conference «Theory and practice of struggle against parasitic diseases»]. Moscow, 2011, pp. 258–260.
3. Kryazhev A.L. Associated infections in cattle in conditions of Vologda region Ассоциативные инвазии. Mater. dokl. nauch. konf. Vseros. o-va gel'mintol. RAN «Teorija i praktika bor'by s parazitarnymi boleznjami». [Proceedings of scientific conference «Theory and practice of struggle against parasitic diseases»]. Moscow, 2011, pp. 260- 263.
4. Kryazhev A.L. Mixed infections in cattle in conditions of Vologda region. Molochnohozjajstvennyj vestnik [Dairy Farming Bulletin], 2011, no. 1, pp. 17–19.
5. Muromtsev A. B. Osnovnye gel'mintozy zhvachnyh zhivotnyh v Kaliningradskoj oblasti (epizootologija, patogenez, lechebno-profilakticheskie meroprijatiya): avtoref. dis. … d-ra vet. nauk [The main helminthosis in ruminants in Kaliningrad region (epizootology, pathogenesis, medical and preventive measures): Abstr. doct. thesis in vet. sciences]. St. Petersburg, 2008. 42 p.
6. Musaev M. B. Izyskanie otechestvennyh preparatov dlja terapii zhivotnyh pri trematodozah i ih antigel'mintnaja i farmakotoksikologicheskaja harakteristika: avtoref. dis. … d-ra vet. nauk
[Exploration of domestic drugs against trematodosis in animals and their anthelmintic and pharmaco- toxicological characteristics : Abstr. doct. thesis in vet. sciences]. – М., 2010. – 48 с.© 2015 The Author(s). Published by All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K.I. Skryabin.
This is an open access article under the Agreement of 02.07.2014 (Russian Science Citation Index (RSCI) and the Agreement of 12.06.2014 (CABI.org / Human Sciences section).