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PATHOGENESIS OF DERMATITIS OF DEMODECOSIS ETIOLOGY IN DOGS
O. Shapovalova* postgraduate
I. G. Glamazdin** doctor of veterinary sciences
N. Yu. Sysoeva* PhD in veterinary sciences
* Moscow State University of Food Production. 109316, Moscow, Talalihin st., 33, e-mail: glamazdin@yandex.ru
** Russian Academy of Staffing of Agroindustrial Complex. 111621, Moscow, Orenburgskaya st. 15 B, room 404
Issues on demodecosis infection in dog population of Moscow have been studied; the dependence between the accents in the pathogenesis and the age and dog breed has been determined. The risk of acute demodecosis increases with the age, and in female dogs such risk goes up during their heat cycles. Biochemical values of the damage to internal organs: the total protein, glucose, urea, creatinine, activity of aspartate aminotransferase (AST) and alanine transaminase (ALT) in dogs’ blood have been estimated. In dogs with low and medium infection rates the average AST and ALT values were 51,05±2,64 and 98,69±3,85 u/l respectively, with a high infection rate 57,31±2,91 and 131,09±3,65 u/l. The increase of creatinine level and decrease in blood glucose of all tested dogs’ groups were observed. The most significant changes were determined in the levels of creatinine and glucose: up to 87,41±3,85 mkmol and 3,91±0,21 mmol respectively. Demodecosis should be considered as a complex issue requiring a detailed examination of enzyme levels and hormonal status.
Keywords: demodecosis, biochemical values, pathogenesis, dogs.
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© 2016 The Author(s). Published by All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K.I. Skryabin.
This is an open access article under the Agreement of 02.07.2014 (Russian Science Citation Index (RSCI)) and the Agreemnt of 12/06/2014 (CABI org / Human Sciences section)