Efficacy of combined niclosamide-based drug against Anoplocephala spp. of different types and ages

EFFICACY OF COMBINED NICLOSAMIDE-BASED DRUG AGAINST ANOPLOCEPHALA SPP.  OF DIFFERENT TYPES AND AGES

A. I. Varlamova PhD in veterinary sciencesI. A. Arkhipov, E. E. Belova doctors of veterinary sciencesAll-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K. I. Skryabin,  117218, Moscow, 28 B. Cheremushkinskaya str, e-mail: arkhipov@vniigis.ru
K. M. Sadov doctor of veterinary sciences
Samara Research Veterinary Station, e-mail: samnivs@mail.ru
V. N. Skira doctor of veterinary sciences
Federal Agency of Scientific Organizations
N. V. Danilevskaya doctor of veterinary sciences
Moscow State Academy of Veterinary Medicine and Biotechnology named after K. I. Skryabin, 109472, Moscow, 23 Academician Skryabin str.,  e-mail: rector@mgavm.ru

Effect of Vigisox, Praziquantel, Fenbendazole, Albendazole and Niclozamide at the doses of 60, 3, 10, 10 and 100 mg/kg respectively applied against Moniezia spp. of different ages in sheep spontaneously infected with Moniezia expansa and M. benedeni is studied. Efficacy of drugs applied against mature Moniezia spp., was the following: Vigisox, Niclozamide and Praziquantel – 100 %, Albendazole – 88, Fenbendazole – 84 %, and against immature Moniezia spp.: Vigisox, Niclozamide – 89,3 %,  Praziquantel – 100, Albendazole – 75 and Fenbendazole – 64,3 % respectively. The results shown a non significant difference in efficacy of Vigisox applied against various types of Anoplocephala spp. The drug at a dose of 60 mg/kg has shown a 97,9 % efficacy against M. expansa, 97,5 % – M. benedeni, 98,9 % – Thysaniezia giardi. While conducting preimaginal dehelminthizations of animals it is necessary to apply anthelmintics taking into account their effect on immature Moniezia spp.

Keywords: sheep, Moniezia spp., Thysaniezia giardi, Vigisox, anthelmintics, efficacy.

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© 2016 The Author(s). Published by All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K.I. Skryabin.
This is an open access article under the Agreement of 02.07.2014 (Russian Science Citation Index (RSCI)) and the Agreemnt of 12/06/2014 (CABI org / Human Sciences section)